Shedding
Their coats shed differently: the Dogo Argentino sheds through the year, the Rottweiler moults most as the seasons change.
Grooming
The Rottweiler needs more grooming, brushing a few times a week, where the Dogo Argentino needs a brush once a week.
Temperament
They differ most on affection (Dogo Argentino: affectionate on its own terms; Rottweiler: a lap or leaning dog) and on independence (Dogo Argentino: decides for itself; Rottweiler: cooperative, with its own ideas).
Alike
They are much the same size as adults, about 42 kg (93 lb) for the Dogo Argentino and 45 kg (99 lb) for the Rottweiler.
Alike
Both are rated the same on loyalty: sticks close to its people.